History[ edit ] Long before a deeper understanding of their numerous biological functions, the plant lectins, also known as phytohemagglutininswere noted for their particular high specificity for foreign glycoconjugates e. It is generally believed that the earliest description of a lectin was given by Peter Hermann Stillmark in his doctoral thesis presented in to the University of Dorpat. Stillmark isolated ricinan extremely toxic hemagglutininfrom seeds of the castor plant Ricinus communis.
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Lectins are carbohydrate-binding proteins, macromolecules that are highly specific for sugar moieties of other molecules. Lectins perform recognition on the cellular and molecular level and play numerous roles in biological recognition phenomena involving cells, carbohydrates, and proteins.